Projected Trades
* Trade: Atlanta Falcons acquire No. 2 overall pick from the St. Louis Rams for No. 6 overall pick, second-round pick in 2014, fourth-round pick in 2014 and second-round pick in 2015.
* Trade: San Francisco 49ers acquire No. 16 overall pick from the Dallas Cowboys for No. 30 overall pick and third-round pick.
First Round | Pick | Team | Player | Position | College | Change |
| 1 | Houston | Blake Bortles | QB | Central Florida | N/A |
| 2 | Atlanta (via St. Louis) | Jedeveon Clowney | DE | South Carolina | N/A |
| 3 | Jacksonville | Khalil Mack | LB | Buffalo | Focused on defense in free agency. Should continue in draft. |
| 4 | Cleveland | Teddy Bridgewater | QB | Louisville | Released Jason Campbell and Brandon Weeden |
| 5 | Oakland | Derek Carr | QB | Fresno State | N/A |
| 6 | St. Louis (via Atlanta) | Jake Matthews | OT | Texas A&M | N/A |
| 7 | Tampa Bay | Greg Robinson | OT | Auburn | Released LT Donald Penn, Signed RT Anthony Collins |
| 8 | Minnesota | C.J. Mosley | LB | Alabama | Retained both Matt Cassel and Christian Ponder |
| 9 | Buffalo | Sammy Watkins | WR | Clemson | Re-signed Scott Chandler |
| 10 | Detroit | Darqueze Dennard | CB | Michigan State | N/A |
| 11 | Tennessee | Johnny Manziel | QB | Texas A&M | Johnny Manziel drops outside of the top 10. |
| 12 | New York (G) | Taylor Lewan | OT | Michigan | No moves at offensive tackle thus far. |
| 13 | St. Louis | Ha Ha Clinton-Dix | S | Alabama | No moves at safety thus far. |
| 14 | Chicago | Re'Shade Hageman | DT | Minnesota | Likely departure of Henry Melton in free agency. |
| 15 | Pittsburgh | Anthony Barr | LB | UCLA | LaMarr Woodley released. |
| 16 | San Francisco (via Dallas) | Mike Evans | WR | Texas A&M | Evans drops down the board, filled need at safety. |
| 17 | Baltimore | Odell Beckham Jr | WR | LSU | N/A |
| 18 | New York (J) | Kelvin Benjamin | WR | Florida State | Eric Decker signing doesn't change much here. |
| 19 | Miami | Zack Martin | OL | Notre Dame | Even after Branden Albert signings, need more help along offensive line. |
| 20 | Arizona | Eric Ebron | TE | North Carolina | Filling holes elsewhere in free agency |
| 21 | Green Bay | Jimmie Ward | S | Northern Illinois | As always, inactivity indicates where draft focus may be |
| 22 | Philadelphia | Justin Gilbert | CB | Oklahoma St. | N/A |
| 23 | Kansas City | Marqise Lee | WR | USC | N/A |
| 24 | Cincinnati | Jason Verrett | CB | Texas Christian | N/A |
| 25 | San Diego | Dee Ford | LB | Auburn | N/A |
| 26 | Cleveland | Brandin Cooks | WR | Oregon State | N/A |
| 27 | New Orleans | Louis Nix III | DT | Notre Dame | N/A |
| 28 | Carolina | Jordan Matthews | WR | Vanderbilt | Steve Smith release and loss of Ted Ginn in free agency. |
| 29 | New England | Troy Niklas | TE | Notre Dame | N/A |
| 30 | Dallas (via SF) | Aaron Donald | DT | Pittsburgh | Losing Jason Hatcher in free agency |
| 31 | Denver | Timmy Jernigan | DT | Florida State | N/A |
| 32 | Seattle | Kony Ealy | DE | Missour | Losses of Chris Clemons and Red Bryant |