Looking at matchups is an important part of the process for setting lineups in fantasy football. You are always targeting that big running back against a weak front-seven or a receiver against a cornerback who gets burned, but there's more to it all.

The Las Vegas odds makers are some of the best in the business, they know the game and set lines accurately. The Pittsburgh Steelers-New England Patriots game is just another great example, the line was set at (-7.5) for New England and they won by seven.