Jacoby Brissett, Quarterback, Indianapolis Colts
Brissett has put up only five total touchdowns compared to four interceptions in fives games (four starts) this season. However, he is coming off a strong 340 total yard performance against the San Francisco 49ers and seems to be getting more comfortable in the Colts' offense after a summe trade from the Patriots. If you're looking for a low-end QB2 option, he could be that guy.
Brian Hoyer, Quarterback, San Francisco 49ers
Hoyer himself might not be a good quarterback, but he surely is taking advantage of Kyle Shanahan's system to be a fantasy-relevant signal caller. The veteran completed 29-of-46 passes for 353 yards with two touchdowns and zero picks against Indy last week. Over the course of the past three games, he's put up nearly 1,000 total yards with five touchdowns and two picks.
Adrian Peterson, Running Back, Arizona Cardinals
As the shock of the AD trade from New Orleans to Arizona wears off, comes the realization that he might in fact be a fantasy relevant option moving forward. Peterson now likely takes over the lead ball-carrier duties for a Cardinals offense that ranks dead last in the NFL in rushing. That's magnified by the fact that Arizona released Chris Johnson immediately after acquiring Peterson. If not now, he's someone to watch on the waiver wire moving forward.
Jerick McKinnon, Running Back, Minnesota Vikings
With Dalvin Cook lost for the season, McKinnon took over lead ball-carrier duties over Latavius Murray in Monday night's win over the Chicago Bears. He put up 146 total yards and a score on 22 touches. Meanwhile, Murray was held to 43 yards on 14 touches. Sure, McKinnon's track record doesn't speak to fantasy relevance. But he has an entirely new offensive line in front of him and looked darn good in his first substantial action of the season. He's worth a flyer here.
Matt Breida, Running Back, San Francisco 49ers
This is what we'd call a claim and stash option. Despite seeing more action on the ground than Carlos Hyde last week, this rookie likely won't take over primary ball-carrier duties with Hyde in the mix. Then again, there's a real chance Hyde, an impending free agent, will be traded in-season. If that's the case, Breida takes over as the obvious starter here. He put up 71 yards on 13 touches against Indy last week and is averaging a solid four yards per rush on the season.
Cooper Kupp, Wide Receiver, Los Angeles Rams
With Sammy Watkins having caught just one pass over the past two games, it's readily apparent that Kupp has become Jared Goff's favorite target in a vastly improved Rams passing offense. Through five games, the rookie has caught 17 passes for 230 yards and two touchdowns. This has him as a mid-tier FLEX option. With 15 targets over the past two games, that level of productivity promises to increase.
Nelson Agholor, Wide Receiver, Philadelphia Eagles
As Alshon Jeffery and Torrey Smith continue to make the headlines more in Philly, this former first-round pick has stepped his game up big time this season. He's coming off a four-catch, 93-yard performance that saw him ready the end zone against Arizona. And thus far this season, Agholor has caught 70 percent of the passes thrown in his direction for 266 yards and three scores. This has him as a mid-tier WR2 through five weeks.
Austin Hooper, Tight End, Atlanta Falcons
He's pretty much been boom or bust. In Week 1 and Week 4 (prior to Atlanta's bye), Hooper put up a combined seven catches for 178 yards and a score. In the two games in between that, he tallied three catches for 16 yards. As Matt Ryan gets more comfortable with his young tight end, we expect his targets numbers to increase. That makes Hooper a potential TE1 option moving forward.