Kansas City Chiefs (6-5) @ New York Jets (4-7)
The struggling Chiefs will be missing a couple of key pieces against the Jets this week. Starting linebacker Dee Ford will miss the game with a back injury. Charcandrick West is also missing the game, although it is not injury related. West is a change-of-pace running back, who gets most of his playing time on third downs and in obvious passing situations. Expect Akeem Hunt to get some more time than usual, but Kareem Hunt will still dominate this backfield. Linebacker Tamba Hali (knee) and wide receiver Albert Wilson (hamstring) are both listed as questionable.
Running back Matt Forte got some practice in this week, but is still listed as questionable with his lingering knee issue. He played through the same injury last week against the Panthers. If Forte does end up missing this game, expect Bilal Powell to start in his place, with Elijah McGuire backing him up.
New England Patriots (9-2) @ Buffalo Bills (6-5)
Wide receiver Chris Hogan will miss his fourth straight game after being ruled out for Sunday's game against the Bills. Expect Brandin Cooks, Danny Amendola, and Rob Gronkowski to absorb most of the targets as usual. Tom Brady popped up on the injury report this week because of his Achilles, but he was removed from the report on Friday and will start on Sunday. Tackle Marcus Cannon (ankle) will not play.
The Bills will also be short a wide receiver. Newly acquired Kelvin Benjamin will miss the game with a knee injury. Star running back LeSean McCoy sat out practice on Friday, but is expected to play this week. Left tackle Cordy Glenn (foot) is out.
Denver Broncos (3-8) @ Miami Dolphins (4-7)
Trevor Siemian will start at quarterback for the Broncos on Sunday after Paxton Lynch was ruled out with the ankle injury he suffered last week against the Raiders. They will also be missing some key contributors on the defensive line, Derek Wolfe (neck) and Domata Peko (knee) have both been ruled out this week. Linebacker Shane Ray is questionable with an illness.
Starting quarterback Jay Cutler will be back on the field this week. He missed last week's game against the Patriots because of a concussion. He has cleared the concussion protocol and will get the start. Backup QB Matt Moore won't be active because of a foot injury, so David Fales will take over backup duties. Running back Kenyan Drake will get to start and see the majority of snaps as Damien Williams is recovering from a shoulder injury.
San Francisco 49ers (1-10) @ Chicago Bears (3-8)
Jimmy Garoppolo will get his first chance to start for the 49ers after they acquired him right before the trade deadline. He steps in for C.J. Beathard, who left last week's game against Seattle with a leg injury. Aside from this, the 49ers look really healthy going into Sunday's game. Tackle Trent Brown and safety Adrian Colbert are listed as questionable, but should be able to play.
The Bears' offense is pretty healthy going into this game. Starting guard Josh Sitton is questionable with a concussion. The defense looks like it will get linebacker Danny Trevathan back after a three game absence. He was removed from the injury report on Friday. Safety Adrian Amos is nursing a hamstring injury and is doubtful to play. Fellow defensive backs Cre'von LeBlanc and Bryce Callahan are listed as questionable.
Detroit Lions (6-5) @ Baltimore Ravens (6-5)
Starting center Travis Swanson has been ruled out after suffering a knee injury against the Vikings on Thanksgiving. Running back Ameer Abdullah was limited in practice with a neck injury. He is officially listed as questionable but should be able to play. If he misses, expect Theo Riddick to get the majority of snaps in the backfield. The Lions special teams will take a hit as rookie return specialist Jamal Agnew will miss his second straight game with knee injury
The only player who has been officially ruled out for the Ravens is backup offensive lineman Jermaine Eluemunor. Starting running back Alex Collins (calf) is questionable. On the defense, CB Marlon Humphrey (thigh), LB C.J. Mosley (ankle), and CB Jimmy Smith (Achilles) are all questionable after a limited practice Friday.
Minnesota Vikings (9-2) @ Atlanta Falcons (7-4)
The Vikings will be missing starting right tackle Mike Remmers, he is nursing a lower back injury. Rashod Hill will get the start in his place. Stud linebacker Eric Kendricks was limited in practice this week with a hip injury. He is listed as questionable but expected to play.
The Falcons are getting their star running back Devonta Freeman back in action this week. He has cleared the concussion protocol and will get the start on Sunday after missing the last two games. Running back Tevin Coleman, who was starting in his absence, will slide back to his backup role. For what the Falcons have gained on offense, they will have to deal with a huge loss on their defense. Star cornerback Desmond Trufant has been ruled out with a concussion. CB Brian Poole was limited in practice with a back injury but will be good to go this Sunday. They'll need him to step up in Trufant's absence.
Tampa Bay Buccaneers (4-7) @ Green Bay Packers (5-6)
Franchise quarterback Jameis Winston will return to the Bucs starting lineup this week. He missed the past three games with an ailing shoulder. He may be missing a couple of weapons, though. RB Doug Martin has been ruled out of Sunday's game with a concussion. Jacquizz Rodgers will get to start in his place. WR DeSean Jackson and TE Cameron Brate are both listed as questionable but both should be able to play. CB Vernon Hargreaves (hamstring), DE Robert Ayers (concussion), S TJ Ward (concussion), DT Clinton McDonald (back), and safety Josh Robinson (hamstring) have all been ruled out.
Brett Hundley will continue to start at quarterback for the packers while Aaron Rodgers sits on IR with a broken collarbone. Ty Montgomery began the year as the Packer's number one running back, but his season is over after being placed on IR due ongoing rib injuries. Jamaal Williams is most likely to get the start at RB this week. Aaron Jones has potential to play, he is a gametime decision as of right now. If he can't play, Williams will carry the load. CB Kevin King (shoulder) will miss this game, while LB Clay Matthews (groin), LB Ahmad Brooks (back, and DT Kenny Clark (ankle) are all questionable.
Houston Texans (4-7) @ Tennessee Titans (7-4)
WR DeAndre Hopkins (foot) and RB Lamar Miller (knee) were left off of the final injury report this week, indicating that both will be able to play and handle a full load on Sunday. WR Will Fuller (ribs) will miss his third straight game.
WR Rishard Matthews (hamstring) returned to practice this week, although he was limited. He is truly questionable and looking like a game-time decision. RB DeMarco Murray missed practice Thursday with an illness, but participated in full on Friday and will start this week.
Indianapolis Colts (3-8) @ Jacksonville Jaguars (7-4)
WR Donte Moncrief appeared on the injury report Thursday with a groin issue. The receiver was able to practice in full on Friday, and should be able to play on Sunday despite his questionable tag. Center Ryan Kelly will miss the game with a concussion. The Colts defense will be without top cornerback Rashaan Melvin (hand) and DT Hasaan Ridgeway (shoulder).
WR Allen Hurns has been ruled out of this game with an ankle injury. Expect rookie WR Dede Westbrook to get some more snaps as a result. Stud linebacker Telvin Smith and offensive tackle Josh Wells will both be sidelined with concussions.
Cleveland Browns (0-11) @ Los Angeles Chargers (5-6)
Although it wasn't due to an injury, WR Josh Gordon will be starting in his first game since 2014 this week against the Chargers. The Browns have said that Gordon will start and that he will not be on a pitch count. The only player on the Browns' injury report is WR Sammie Coates who is out with a leg injury.
Rookie WR Mike Williams will not play this week as he nurses a knee injury. The Chargers' first round pick this past draft has had a hard time staying on the field in his debut season. Stud cornerback Casey Hayward is questionable, but it is not injury related. Kicker Nick Novak (back) and DT Corey Liuget (toe) are both questionable.
Los Angeles Rams (8-3) @ Arizona Cardinals (5-6)
The Rams will be without WR Robert Woods again this week. Head coach Sean McVay said the target for his return is week 15 against the Seahawks. Sammy Watkins and Cooper Kupp will be the main targets for QB Jared Goff this week with Woods sidelined. LB Connor Barwin is out with a forearm injury. Running backs Malcolm Brown and Lance Dunbar are both questionable with hurt knees.
Starting running back Adrian Peterson is questionable this week with a neck injury. It is sounding like he will be a game-time decision after failing to log a single practice this week. If all day can't suit up, D.J. Foster should take over in the backfield. DT Josh Mauro (ankle) and TE Troy Niklas (back and knee) are also questionable. WR John Brown (toe), LB Deone Bucannon (ankle) and DT Corey Peters (ankle) have all been ruled out of this contest.
New York Giants (2-9) @ Oakland Raiders (5-6)
QB Eli Manning isn't injured, but he is not getting the start this week. Head coach Ben Mcadoo announced that QB Geno Smith will start this Sunday in Oakland. This will be his first start as a member of the Giants. It looks like WR Sterling Shepard will return to action this week, he was left off of the final injury report. OT Justin Pugh (back) and LB Jonathan Casillas (neck and wrist) are both ruled out, while CB Eli Apple (hip) and DT Damon Harrison (arm) are questionable.
The Raiders will be missing their top two receivers this week. Michael Crabtree is suspended for this game after his scuffle with Aqib Talib and the Broncos last week. Amari Cooper suffered a concussion and an ankle injury on the same play last week. He is ruled out. CB David Amerson and WR Cordarrelle Patterson (hip) are both questionable, but should be able to play.
Carolina Panthers (8-3) @ New Orleans Saints (8-3)
WR Devin Funchess appeared on the Panthers' injury report earlier this week with a hurt toe. He has since been removed from the report and will start on Sunday. Rookie RB Christian McCaffrey is listed as questionable with a shoulder injury. He should be able to play despite this status. Tight end Greg Olsen is also questionable after reaggravating the foot injury that kept him out for several weeks already this season. Center Ryan Kalil (neck), LB Thomas Davis (hamstring) and LB Shaq Thompson (foot) are all questionable.
Rookie corner Marshon Lattimore was able to participate in a limited practice on Friday and is questionable for Sunday. Fellow corner P.J. Williams (shoulder) and tackle Terron Armstead (thigh) are also questionable, while tight end Coby Fleener (concussion) and safety Marcus Williams(groin) are ruled out.
Philadelphia Eagles (10-1) @ Seattle Seahawks (7-4)
The Seahawks have a slew of injuries on both sides of the ball. On the offense, tackle Duane Brown is questionable with an ankle injury. Guard Oday Aboushi has been ruled out with a hurt shoulder. Tight end Jimmy Graham is questionable with an ankle injury of his own, but fully expected to start. On the defense, CB Richard Sherman and S Kam Chancellor are both already ruled out for the season. S Earl Thomas is also banged up, nursing a heel injury. He is expected to play despite being marked questionable. Bobby Wagner (hamstring) is questionable. Defensive linemen Dion Jordan and Nazair Jones have been ruled out with a neck and ankle injury respectively.
Pittsburgh Steelers (9-2) @ Cincinnati Bengals (5-6)
Star WR Antonio Brown sat out Friday's practice this week with a toe injury. It has been reported that this injury is very minor and should not affect his ability to play on Monday. Returning will be rookie WR JuJu Smith-Schuster, who missed last week's game against the Packers with a hamstring injury. A key contributor on defense, LB Ryan Shazier has not practiced yet this week. He is nursing an injured ankle and is currently questionable for Monday night.
The Bengals' had their own star WR on the injury report this week. A.J. Green was limited Friday due to an illness. He should be ready for a full workload Monday night. TE Tyler Kroft practiced in full on Friday and should also be good to go for this game. The Bengals expect linebackers Vincent Rey (hamstring) and Nick Vigil (ankle) to miss the game. Safety Shawn Williams is also expected to be out with a hamstring injury of his own.