Patriots at Bills

The New England Patriots get a chance to avenge their lone defeat of the season when they visit Rex Ryan and the Buffalo Bills on Sunday in a matchup of AFC East rivals. The Bills shocked the Patriots in Week 4, handing New England its first shutout loss at Gillette Stadium with Tom Brady serving the finale of his four-game suspension.

"It was a great time to play them," Ryan said of the first matchup. "You know, I'll admit it. It was probably an easier game to play them without (Brady)." That earlier victory against the Patriots was part of a four-game winning streak for Buffalo that was snapped in last week's 28-25 loss at Miami. New England was forced to start third-stringer Jacoby Brissett in the earlier meeting against the Bills, but it has ripped off three straight double-digit victories since Brady returned to the lineup. Brady owns a staggering 25-3 record against Buffalo, including a sweep last season that featured victory margins of eight and seven points.

TV: 1 p.m. ET, CBS. LINE: Patriots -6. O/U: 47

ABOUT THE BILLS (4-3): Buffalo posted a victory margin of nearly 18 points during the four-game winning streak, but struggled in Miami with its top offensive weapon hobbled. LeSean McCoy, who rushed for 470 yards and five touchdowns during the four-game run, managed only 11 yards against the Dolphins while battling a balky hamstring that kept him out of practice Thursday. Quarterback Tyrod Taylor, who threw for 246 yards and a touchdown in the earlier meeting, could be without Marquise Goodwin (concussion) and Robert Woods (foot), as well as Sammy Watkins, who is on injured reserve. The Bills were gouged for 256 rushing yards by the Dolphins, but defensive tackle Marcell Dareus is expected back after missing three games.

ABOUT THE PATRIOTS (6-1): New England leaned heavily on the run in a 27-16 win at Pittsburgh last week, with bruising back LeGarrette Blount rushing for 127 yards and a pair of touchdowns. Blount was held in check in the first meeting, managing 54 yards on 13 carries, but Brady will likely come out throwing after amassing 1,004 yards, eight touchdowns and zero interceptions in his first three starts. Tight end Rob Gronkowski, who missed the first two games due to injury, has 16 receptions for 364 yards and two scores since Brady's return while running back James White has 14 catches and three TDs during the same span. The Patriots' defense is vulnerable, giving up 258.7 yards per game, but it also is permitting an AFC-low 15.3 points.

OVERTIME

1. Brady can tie Brett Favre for the most wins (26) against one opponent since the NFL merger.

2. Bills LB Lorenzo Alexander leads the NFL with nine sacks.

3. Gronkowski has 68 career touchdowns and can set the franchise record with one more.
Poll

Who will win this game?

Odds
SpreadMoneylineMoneyTotal
Buffalo BillsBills+1 12  -110125
67.50
o -120u -120
New England PatriotsPatriots-1 12  -110-145
Spread Consensus: Buffalo Bills: 32.47%     New England Patriots: 67.53%
Vegas Prediction: Buffalo: 33 (Loss)    New England: 35 (Win)
Season Series
BuffaloStatsNew England
2-3Vs3-2
100Points106
12Touchdowns10
6/8Field Goals12/15
110/166 (1090 yd.)Passing120/195 (1399 yd.)
145 CAR (560 yd.)Rushing111 CAR (397 yd.)