Bills 34, Jaguars 18
Ryan Fitzpatrick threw for two touchdowns and ran for another as host Buffalo kept its postseason hopes alive.
Fitzpatrick threw for only 112 yards but guided the Bills (5-7) to 27 unanswered points to turn a 10-7 deficit into a 34-10 lead with 13:29 left in the game.
C.J. Spiller rushed for 77 yards and a touchdown and Fred Jackson ran for 109 yards on 25 carries as Buffalo amassed 232 yards on the ground in dealing Jacksonville (2-10) its eighth loss in nine games.
Jaguars quarterback Chad Henne, in his second start since replacing Blaine Gabbert, finished 18-of-41 for 208 yards with one touchdown and one interception. He ran for a score but was sacked four times and lost a fumble.
The Bills went ahead to stay on Fitzpatrick's 11-yard scoring pass to Scott Chandler with 1:56 left in the second quarter and extended the lead to 17-10 at the half on Rian Lindell's 29-yard field goal, which came after Mario Williams sacked Henne and forced a fumble.
GAME NOTEBOOK: Fitzpatrick opened the scoring with a quarterback sneak for his first rushing TD since Nov. 29, 2009. ... Jaguars RB Rashad Jennings was knocked out of the game with a concussion early in the second quarter. With Maurice Jones-Drew and Jalen Parmele already out with injuries, Jacksonville was forced to go with Montell Owens, who did not have a carry this season entering the contest. ... Lindell's 50-yard FG in the third quarter was his longest since he connected from the same distance at Baltimore on Oct. 24, 2010.