Colts 49, Redskins 27

Andrew Luck threw a career-high five touchdowns - two apiece to Coby Fleener and Donte Moncrief - as Indianapolis posted a home victory against Washington.

In a game that originally was hyped as Luck versus Robert Griffin III - the first two picks in the 2012 draft - the matchup lost a bit of its luster this week when Washington (3-9) benched Griffin in favor of Colt McCoy, who passed for a career-high 392 yards and three touchdowns. Luck, meanwhile, was 19-of-27 for 370 yards - his 10th game this season with at least 300 yards through the air.

Moncrief caught three passes for a career-high 134 yards while Fleener racked up 127 yards on four catches as the Colts (8-4) won for the third time in four games. T.Y. Hilton also caught a TD pass and Daniel Herron rushed for 88 yards and a touchdown for Indianapolis, which converted 5-of-8 third-down attempts.

The hosts began to create separation with three touchdowns in a 5 1/2-minute stretch of the third quarter - a 48-yard pass from Luck to Moncrief, a 35-yard fumble recovery for a score by D'Qwell Jackson and a 73-yard strike from Luck to Fleener, who broke two tackles en route to the end zone to push the Colts' lead to 42-24. Kai Forbath's 29-yard field goal got the Redskins within 42-27 early in the fourth, but Luck answered less than 90 seconds later with a 79-yard strike to Moncrief to restore a commanding lead.

Luck's 30-yard TD pass to Fleener initially put the Colts ahead 7-3 midway through the first before Herron's 49-yard scoring run and Luck's short TD pass to Hilton made it 21-3. McCoy found Roy Helu for a 21-yard score late in the second quarter and connected with Logan Paulsen from 16 yards out early in the third to make it 21-17 before Indianapolis pulled away.

GAME NOTEBOOK: Luck became the fastest quarterback to reach 12,000 career passing yards, doing it in only 44 games. He also became the third Colts quarterback to throw for 4,000 yards in a season, joining Hall of Famer Johnny Unitas and future Canton inductee Peyton Manning. ... Redskins TE Jordan Reed, who missed last week's contest with a hamstring injury, returned to collect a team-high 123 yards on nine receptions. ... Washington RB Alfred Morris was limited to 67 yards on 17 carries as the Redskins lost their fourth straight game.
Final1st2nd3rd4thScore
Indianapolis ColtsColts71421749
Washington CommandersCommanders3714327
Indianapolis
Passing:Andrew Luck 19/27 (370 YDS)
Rushing:Boom Herron 8 CAR (88 YDS)
Receiving:Donte Moncrief 3 REC (134 YDS)
Washington
Passing:Colt McCoy 31/47 (392 YDS)
Rushing:Alfred Morris 17 CAR (67 YDS)
Receiving:Jordan Reed 9 REC (123 YDS)