WEEKDATETIME (ET)TIME (ET)HOME TEAMHOMEVISITOR TEAMVISITORNOTES
Pre-Season Week 1Sat Aug 9th 2025Aug 9th
1:00 PM		1:00 PM Buffalo Bills Bills New York Giants Giants NYG 34 @ BUF 25 | Recap
Pre-Season Week 2Sun Aug 17th 2025Aug 17th
8:00 PM		8:00 PM Chicago Bears Bears Buffalo Bills Bills BUF 0 @ CHI 38 | Recap
Pre-Season Week 3Sat Aug 23rd 2025Aug 23rd
7:30 PM		7:30 PM Tampa Bay Buccaneers Buccaneers Buffalo Bills Bills BUF 23 @ TB 19 | Recap
Week 1Sun Sep 7th 2025Sep 7th
8:20 PM		8:20 PM Buffalo Bills Bills Baltimore Ravens Ravens BAL 40 @ BUF 41 | Recap
Week 2Sun Sep 14th 2025Sep 14th
1:00 PM		1:00 PM New York Jets Jets Buffalo Bills Bills BUF 30 @ NYJ 10 | Recap
Week 3Thu Sep 18th 2025Sep 18th
8:15 PM		8:15 PM Buffalo Bills Bills Miami Dolphins Dolphins MIA 21 @ BUF 31 | Recap
Week 4Sun Sep 28th 2025Sep 28th
1:00 PM		1:00 PM Buffalo Bills Bills New Orleans Saints Saints NO 19 @ BUF 31 | Recap
Week 5Sun Oct 5th 2025Oct 5th
8:20 PM		8:20 PM Buffalo Bills Bills New England Patriots Patriots NE 23 @ BUF 20 | Recap
Week 6Mon Oct 13th 2025Oct 13th
7:15 PM		7:15 PM Atlanta Falcons Falcons Buffalo Bills Bills BUF 14 @ ATL 24 | Recap
Week 8Sun Oct 26th 2025Oct 26th
1:00 PM		1:00 PM Carolina Panthers Panthers Buffalo Bills Bills BUF 40 @ CAR 9 | Recap
Week 9Sun Nov 2nd 2025Nov 2nd
4:25 PM		4:25 PM Buffalo Bills Bills Kansas City Chiefs Chiefs KC 21 @ BUF 28 | Recap
Week 10Sun Nov 9th 2025Nov 9th
1:00 PM		1:00 PM Miami Dolphins Dolphins Buffalo Bills Bills BUF 13 @ MIA 30 | Recap
Week 11Sun Nov 16th 2025Nov 16th
1:00 PM		1:00 PM Buffalo Bills Bills Tampa Bay Buccaneers Buccaneers TB 32 @ BUF 44 | Recap
Week 12Thu Nov 20th 2025Nov 20th
8:15 PM		8:15 PM Houston Texans Texans Buffalo Bills Bills BUF 19 @ HOU 23 | Recap
Week 13Sun Nov 30th 2025Nov 30th
4:25 PM		4:25 PM Pittsburgh Steelers Steelers Buffalo Bills Bills BUF 26 @ PIT 7 | Recap
Week 14Sun Dec 7th 2025Dec 7th
1:00 PM		1:00 PM Buffalo Bills Bills Cincinnati Bengals Bengals CIN 34 @ BUF 39 | Recap
Week 15Sun Dec 14th 2025Dec 14th
1:00 PM		1:00 PM New England Patriots Patriots Buffalo Bills Bills BUF 35 @ NE 31 | Recap
Week 16Sun Dec 21st 2025Dec 21st
1:00 PM		1:00 PM Cleveland Browns Browns Buffalo Bills Bills BUF 23 @ CLE 20 | Recap
Week 17Sun Dec 28th 2025Dec 28th
4:25 PM		4:25 PM Buffalo Bills Bills Philadelphia Eagles Eagles PHI 13 @ BUF 12 | Recap
Week 18Sun Jan 4th 2026Jan 4th
4:25 PM		4:25 PM Buffalo Bills Bills New York Jets Jets NYJ 8 @ BUF 35 | Recap
WildcardSun Jan 11th 2026Jan 11th
1:00 PM		1:00 PM Jacksonville Jaguars Jaguars Buffalo Bills Bills BUF 27 @ JAC 24 | Recap
Divisional PlayoffsSat Jan 17th 2026Jan 17th
4:30 PM		4:30 PM Denver Broncos Broncos Buffalo Bills Bills BUF 30 @ DEN 33 | Recap