WEEKDATETIME (ET)TIME (ET)HOME TEAMHOMEVISITOR TEAMVISITORNOTES
Pre-Season Week 1Sat Aug 9th 2025Aug 9th
8:30 PM		8:30 PM San Francisco 49ers 49ers Denver Broncos Broncos DEN 30 @ SF 9 | Recap
Pre-Season Week 2Sat Aug 16th 2025Aug 16th
4:05 PM		4:05 PM Las Vegas Raiders Raiders San Francisco 49ers 49ers SF 22 @ LV 19 | Recap
Pre-Season Week 3Sat Aug 23rd 2025Aug 23rd
8:30 PM		8:30 PM San Francisco 49ers 49ers Los Angeles Chargers Chargers LAC 23 @ SF 30 | Recap
Week 1Sun Sep 7th 2025Sep 7th
4:05 PM		4:05 PM Seattle Seahawks Seahawks San Francisco 49ers 49ers SF 17 @ SEA 13 | Recap
Week 2Sun Sep 14th 2025Sep 14th
1:00 PM		1:00 PM New Orleans Saints Saints San Francisco 49ers 49ers SF 26 @ NO 21 | Recap
Week 3Sun Sep 21st 2025Sep 21st
4:25 PM		4:25 PM San Francisco 49ers 49ers Arizona Cardinals Cardinals ARI 15 @ SF 16 | Recap
Week 4Sun Sep 28th 2025Sep 28th
4:05 PM		4:05 PM San Francisco 49ers 49ers Jacksonville Jaguars Jaguars JAC 26 @ SF 21 | Recap
Week 5Thu Oct 2nd 2025Oct 2nd
8:15 PM		8:15 PM Los Angeles Rams Rams San Francisco 49ers 49ers SF 26 @ LAR 23 | Recap
Week 6Sun Oct 12th 2025Oct 12th
4:25 PM		4:25 PM Tampa Bay Buccaneers Buccaneers San Francisco 49ers 49ers SF 19 @ TB 30 | Recap
Week 7Sun Oct 19th 2025Oct 19th
8:20 PM		8:20 PM San Francisco 49ers 49ers Atlanta Falcons Falcons ATL 10 @ SF 20 | Recap
Week 8Sun Oct 26th 2025Oct 26th
1:00 PM		1:00 PM Houston Texans Texans San Francisco 49ers 49ers SF 15 @ HOU 26 | Recap
Week 9Sun Nov 2nd 2025Nov 2nd
1:00 PM		1:00 PM New York Giants Giants San Francisco 49ers 49ers SF 34 @ NYG 24 | Recap
Week 10Sun Nov 9th 2025Nov 9th
4:25 PM		4:25 PM San Francisco 49ers 49ers Los Angeles Rams Rams LAR 42 @ SF 26 | Recap
Week 11Sun Nov 16th 2025Nov 16th
4:05 PM		4:05 PM Arizona Cardinals Cardinals San Francisco 49ers 49ers SF 41 @ ARI 22 | Recap
Week 12Mon Nov 24th 2025Nov 24th
8:15 PM		8:15 PM San Francisco 49ers 49ers Carolina Panthers Panthers CAR 9 @ SF 20 | Recap
Week 13Sun Nov 30th 2025Nov 30th
1:00 PM		1:00 PM Cleveland Browns Browns San Francisco 49ers 49ers SF 26 @ CLE 8 | Recap
Week 15Sun Dec 14th 2025Dec 14th
4:25 PM		4:25 PM San Francisco 49ers 49ers Tennessee Titans Titans TEN 24 @ SF 37 | Recap
Week 16Mon Dec 22nd 2025Dec 22nd
8:15 PM		8:15 PM Indianapolis Colts Colts San Francisco 49ers 49ers SF 48 @ IND 27 | Recap
Week 17Sun Dec 28th 2025Dec 28th
8:20 PM		8:20 PM San Francisco 49ers 49ers Chicago Bears Bears CHI 38 @ SF 42 | Recap
Week 18Sat Jan 3rd 2026Jan 3rd
8:00 PM		8:00 PM San Francisco 49ers 49ers Seattle Seahawks Seahawks SEA 13 @ SF 3 | Recap
WildcardSun Jan 11th 2026Jan 11th
4:30 PM		4:30 PM Philadelphia Eagles Eagles San Francisco 49ers 49ers SF 23 @ PHI 19 | Recap
Divisional PlayoffsSat Jan 17th 2026Jan 17th
8:00 PM		8:00 PM Seattle Seahawks Seahawks San Francisco 49ers 49ers SF 6 @ SEA 41 | Recap