White Sox at Pirates

The Pittsburgh Pirates own the best interleague record in the majors and have beefed up that mark at the expense of the Chicago White Sox. The Pirates have won seven in a row against Chicago and look to complete a two-game sweep of the visiting White Sox for the second time in as many weeks when the teams square off Wednesday afternoon at PNC Park.

Pittsburgh improved to 11-2 against American League foes with a 7-0 drubbing of Chicago on Tuesday night but saw two starters exit the game with injuries. Starling Marte left after the first inning due to discomfort in his right side and catcher Francisco Cervelli did not return after he was hit by a pitch for the Pirates, who also lead the majors with seven shutouts. The return of Yoan Moncada from the disabled list did nothing to change the sagging fortunes of Chicago, which tumbled to a major league-worst 10-28 mark. It was the fifth shutout loss of the season and the 12th defeat in the last 14 games for the White Sox, who have been burned for 23 runs in the three losses to Pittsburgh.

TV: 12:35 p.m. ET, MLB Network, NBCS Chicago

PITCHING MATCHUP: White Sox LH H├ęctor Santiago (0-1, 5.60 ERA) vs. Pirates RH Jameson Taillon (2-3, 4.08)

Santiago has been used primarily out of the bullpen, with nine of his 11 appearances in relief this season. The 30-year-old will look to purge the memory of his last start, when he was hammered for eight runs on six hits and six walks in a 8-4 loss to the Minnesota Twins on May 5. Corey Dickerson is 2-for-6 against Santiago, who tossed one hitless inning in relief against the Pirates on May 8.

Taillon had to exit his last start due to a laceration on his middle finger after limiting San Francisco to one hit and striking out five over three scoreless innings. He worked five innings of one-run ball in a no-decision at Milwaukee in his previous turn and appears to be back on track after giving up 15 runs during a three-start slide. Taillon will be making his first career start versus Chicago.

WALK-OFFS

1. Marte extended his hitting streak to nine games before leaving Tuesday's contest.

2. White Sox 1B Jose Abreu is 10-for-23 during a six-game hitting streak.

3. Pirates 1B Josh Bell has eight RBIs in his last seven games after knocking in three runs in the series opener.
Odds
SpreadMoneylineMoneyTotal
Chicago White SoxWhite Sox+1 12  -429130
7.50
o 230u -333
Pittsburgh PiratesPirates-1 12  290-170
Moneyline Consensus: Pittsburgh Pirates: 0%     Chicago White Sox: 0%
Vegas Prediction: Pittsburgh: 5 (Win)    Chi. White Sox: 3 (Loss)
Season Series
PittsburghStatsChi. White Sox
4-0Vs0-4
.274Batting Average.257
6.5Runs / Game3.3
4Home Runs6
0Errors1